Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Is immune escape via human leukocyte antigen expression clinically relevant in chronic lymphocytic leukemia? Focus on the controversies.

Leukemia research - 1 Apr 2013

Guillaume Nicolas, Marolleau Jean-Pierre

Abstract excerpt

Changes in classical and non-classical human leukocyte antigen expression by tumor cells can play a critical role in the generation of tumor antigen-specific immune responses and can modulate the interactions of natural killer cells and T cell subpopulations with target cells. Recently, several studies have investigated the relations between HLA molecules and prognosis in B-CLL, suggesting a potential clinical...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Down-Regulation
Share to Histocompatibility Antigens Class I

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Homozygote

Share to Leukemia, Lymphocytic, Chronic, B-Cell

Share to Loss of Heterozygosity

Share to Prognosis

Share to Receptors, Natural Killer Cell

Share to Tumor Escape

Source

Identifiers

PMID: 23347904
DOI: 10.1016/j.leukres.2012.12.021

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Is immune escape via human leukocyte antigen expression clinically relevant in chronic lymphocytic leukemia? Focus on the controversies.PMID 23347904Read ↗

HLA-G is a component of the chronic lymphocytic leukemia escape repertoire to generate immune suppression: impact of the HLA-G 14 base pair (rs66554220) polymorphismSemantic proximity Read ↗

HLA-G expression in B chronic lymphocytic leukemia: a new prognostic marker?Semantic proximity Read ↗

HLA-G protein expression as a potential immune escape mechanism in classical Hodgkin's lymphoma.Semantic proximity Read ↗

Loss or downregulation of HLA class I expression at the allelic level in acute leukemia is infrequent but functionally relevant, and can be restored by interferonSemantic proximity Read ↗

Branched I antigen regulated cell susceptibility against natural killer cytotoxicity through its N-linked glycosylation and overall expression.Semantic proximity Read ↗

HLA-E allelic genotype correlates with HLA-E plasma levels and predicts early progression in chronic lymphocytic leukemia.Semantic proximity Read ↗

Expression of natural killer cell activating receptors in patients with chronic lymphocytic leukaemia.Semantic proximity Read ↗

Down-regulation of HLA-A and HLA-Bw6, but not HLA-Bw4, allospecificities in leukemic cells: an escape mechanism from CTL and NK attack?Semantic proximity Read ↗

NK cell activating ligands on human malignant cells: molecular and functional defects and potential clinical relevance.Semantic proximity Read ↗

Recognition of minor histocompatibility antigens on lymphocytic and myeloid leukemic cells by cytotoxic T-cell clonesSemantic proximity Read ↗

Adhesion molecule expression on B-cells from acute and chronic lymphoid leukemias.Semantic proximity Read ↗

HLA-G expression and role in advanced-stage classical Hodgkin lymphoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.