Article
Expression of natural killer cell activating receptors in patients with chronic lymphocytic leukaemia.
Immunology - 1 Feb 2012
Costello Régis T, Knoblauch Benjamin, Sanchez Carole, Mercier Delphine, Le Treut Thérèse, Sébahoun Gérard
Abstract excerpt
Recent advances in chronic lymphocytic leukaemia (CLL) treatment, more particularly through upfront use of anti-CD20 monoclonal antibodies, have prolonged patient progression-free survival. Nonetheless, apart from allogeneic stem cell transplantation, no curative treatment is available. One possible explanation for the lack of cure in CLL could be a defective immune anti-tumour response. As the result of abnormal...
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