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Article

Genomic variations associated with attenuation in Mycobacterium avium subsp. paratuberculosis vaccine strains.

BMC microbiology - 22 Jan 2013

Bull Tim J, Schock Alex, Sharp J Michael, Greene Mandisa, McKendrick Iain J, Sales Jill, Linedale Richard, Stevenson Karen

Abstract excerpt

BACKGROUND: Mycobacterium avium subspecies paratuberculosis (MAP) whole cell vaccines have been widely used tools in the control of Johne's disease in animals despite being unable to provide complete protection. Current vaccine strains derive from stocks created many decades ago; however their genotypes, underlying mechanisms and relative degree of their attenuation are largely unknown. RESULTS: Using mouse...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23339684
DOI: 10.1186/1471-2180-13-11
PMCID: PMC3599157

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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