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Article

[JAK2 exon 12 mutations in patients with Philadelphia (Ph) chromosome-negative myeloproliferative neoplasms].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 Sept 2012

Wang Jie-Yu, Ai Xiao-Fei, Xu Jun-Qing, Li Qing-Hua, Xu Ze-Feng, Qin Tie-Jun, Zang Yue, Xiao Zhi-Jian

Abstract excerpt

OBJECTIVE: To investigate JAK2 exon 12 mutations in patients with Philadelphia (Ph) chromosome-negative myeloproliferative neoplasms (MPN) and the clinical characteristics of patients with JAK2 exon 12 mutants. METHODS: Allele-specific PCR (AS-PCR) was applied to identify JAK2 V617F mutation. Genomic DNA corresponding to exon 12 of JAK2 gene and epigenetic regulator gene (TET2, ASXL1, EZH2) were amplified by...

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Source

Identifiers

PMID: 23336221
DOI: 10.3760/cma.j.issn.0253-2727.2012.09.004

Genes

JAK2
ASXL1
EPO
TET2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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