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Article

Heterozygous deficiency of endoglin decreases insulin and hepatic triglyceride levels during high fat diet.

PloS one - 1 Jan 2013

Beiroa Daniel, Romero-Picó Amparo, Langa Carmen, Bernabeu Carmelo, López Miguel, López-Novoa José M, Nogueiras Ruben, Diéguez Carlos

Abstract excerpt

Endoglin is a transmembrane auxiliary receptor for transforming growth factor-beta (TGF-beta) that is predominantly expressed on proliferating endothelial cells. It plays a wide range of physiological roles but its importance on energy balance or insulin sensitivity has been unexplored. Endoglin deficient mice die during midgestation due to cardiovascular defects. Here we report for first time that heterozygous...

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Identifiers

PMID: 23336009
DOI: 10.1371/journal.pone.0054591
PMCID: PMC3545959

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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