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Article

Spheroid culture of primary lung cancer cells with neuregulin 1/HER3 pathway activation.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Feb 2013

Endo Hiroko, Okami Jiro, Okuyama Hiroaki, Kumagai Toru, Uchida Junji, Kondo Jumpei, Takehara Tetsuo, Nishizawa Yasuko, Imamura Fumio, Higashiyama Masahiko, Inoue Masahiro

Abstract excerpt

INTRODUCTION: Primary culture of cancer cells is expected to be useful for investigating the biology of cancer and predicting chemosensitivity for individual patients, yet has been hampered by technical difficulties. We recently developed the cancer tissue-originated spheroid (CTOS) method for th...

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Source

Identifiers

PMID: 23328545
DOI: 10.1097/JTO.0b013e3182779ccf

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23328545-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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