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Article

3D cultivation of non-small-cell lung cancer cell lines using four different methods.

Journal of cancer research and clinical oncology - 23 Oct 2024

Malmros Karina, Kirova Nadi, Kotarsky Heike, Carlsén Daniel, Mansour Mohammed S I, Magnusson Mattias, Prabhala Pavan, Brunnström Hans

Abstract excerpt

PURPOSE: The aim of this study was to set up reliable and reproducible culture conditions for 3D tumoroids derived from non-small cell lung cancer (NSCLC) cell lines to enable greater opportunity for successful cultivation of patient-derived samples. METHODS: Four NSCLC cell lines, two adenocarcinomas (A549, NCI-H1975) and two squamous cell carcinomas (HCC-95, HCC-1588), were first cultured in traditional 2D...

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Identifiers

PMID: 39441367
DOI: 10.1007/s00432-024-06003-x
PMCID: PMC11499447

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