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Article

Short-term spheroid culture of primary colorectal cancer cells as an in vitro model for personalizing cancer medicine

6 Sept 2017

Abstract excerpt

Chemotherapy treatment of cancer remains a challenge due to the molecular and functional heterogeneity displayed by tumours originating from the same cell type. The pronounced heterogeneity makes it difficult for oncologists to devise an effective therapeutic strategy for the patient. One approach for increasing treatment efficacy is to test the chemosensitivity of cancer cells obtained from the patient's tumour....

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PMID: 28877221
DOI: 10.1371/journal.pone.0183074

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