Article
Clinical validity of cytochrome P450 metabolism and serotonin gene variants in psychiatric pharmacotherapy
1 Oct 2013
Abstract excerpt
Adverse events, response failures and medication non-compliance are common in patients receiving medications for the treatment of mental illnesses. A systematic literature review assessed whether pharmacokinetic (PK) or pharmacodynamic (PD) responses to 26 commonly prescribed antipsychotic and antidepressant medications, including efficacy or side effects, are associated with nucleotide polymorphisms in eight...
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