Article
Epistatic effects of immunoglobulin GM and KM allotypes on outcome of infection with hepatitis C virus.
Journal of virology - 1 May 2004
Pandey Janardan P, Astemborski Jacquie, Thomas David L
Abstract excerpt
Immunoglobulin GM and KM allotypes-genetic markers of gamma and kappa chains, respectively-are associated with immune responsiveness to several infectious pathogens and with survival in certain viral epidemics. We hypothesized that GM and KM allotypes affect the outcome of hepatitis C virus (HCV) infection. To test this hypothesis, we serologically allotyped 100 persons with well-documented clearance of HCV...
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