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Article

Calcineurin phosphatase activity regulates Varicella-Zoster Virus induced cell-cell fusion.

PLoS pathogens - 1 Nov 2020

Zhou Momei, Kamarshi Vivek, Arvin Ann M, Oliver Stefan L

Abstract excerpt

Cell-cell fusion (abbreviated as cell fusion) is a characteristic pathology of medically important viruses, including varicella-zoster virus (VZV), the causative agent of chickenpox and shingles. Cell fusion is mediated by a complex of VZV glycoproteins, gB and gH-gL, and must be tightly regulated to enable skin pathogenesis based on studies with gB and gH hyperfusogenic VZV mutants. Although the function of gB...

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Identifiers

PMID: 33216797
DOI: 10.1371/journal.ppat.1009022
PMCID: PMC7717522

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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