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Article

Rare missense neuronal cadherin gene (CDH2) variants in specific obsessive-compulsive disorder and Tourette disorder phenotypes.

European journal of human genetics : EJHG - 1 Aug 2013

Moya Pablo R, Dodman Nicholas H, Timpano Kiara R, Rubenstein Liza M, Rana Zaker, Fried Ruby L, Reichardt Louis F, Heiman Gary A, Tischfield Jay A, King Robert A, Galdzicka Marzena, Ginns Edward I, Wendland Jens R

Abstract excerpt

The recent finding that the neuronal cadherin gene CDH2 confers a highly significant risk for canine compulsive disorder led us to investigate whether missense variants within the human ortholog CDH2 are associated with altered susceptibility to obsessive-compulsive disorder (OCD), Tourette disorder (TD) and related disorders. Exon resequencing of CDH2 in 320 individuals identified four non-synonymous...

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Source

Open in PubMed Open full text

Identifiers

PMID: 23321619
DOI: 10.1038/ejhg.2012.245
PMCID: PMC3722668

Genes

CDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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