The spectrum of β-thalassemia mutations in Gaza Strip, Palestine.

doi:10.1016/j.bcmd.2012.12.004

Article

The spectrum of β-thalassemia mutations in Gaza Strip, Palestine.

Blood cells, molecules & diseases - 1 Apr 2013

Sirdah Mahmoud M, Sievertsen Jürgen, Al-Yazji Mansour S, Tarazi Issa S, Al-Haddad Ramy M, Horstmann Rolf D, Timmann Christian

Abstract excerpt

BACKGROUND: β-Thalassemia is a disorder caused by mutations at the hemoglobin β-gene (HBB) locus. Its most important manifestation, the major form, is characterized by severe hypochromic and hemolytic anemia and is inherited in an autosomal recessive mode. In Gaza Strip, Palestine 0.02% of the po...

Topics

Exons
Gene Frequency
Genotype
Humans
Middle East
Mutation
beta-Globins
beta-Thalassemia

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