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Article

Ex vivo evaluation of imatinib mesylate for induction of cell death on canine neoplastic mast cells with mutations in c-Kit exon 11 via apoptosis.

Veterinary research communications - 1 Jun 2013

Rossi Giacomo, Bertani Chiara, Mari Subeide, Marini Carlotta, Renzoni Giacomo, Ogilvie Gregory, Magi Gian Enrico

Abstract excerpt

Several studies of canine spontaneous mast cell tumours have described mutations in the c-kit proto-oncogene. These mutations produce a constitutively activated product and have been suggested to play a role in the malignant transformation of mast cells. We hypothesize that the selective tyrosine...

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Identifiers

PMID: 23315207
DOI: 10.1007/s11259-013-9550-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23315207-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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