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Article

The association of a variant in the cell cycle control gene CCND1 and obesity on the development of asthma in the Swiss SAPALDIA study.

The Journal of asthma : official journal of the Association for the Care of Asthma - 1 Mar 2013

Thun Gian Andri, Imboden Medea, Berger Wolfgang, Rochat Thierry, Probst-Hensch Nicole M

Abstract excerpt

OBJECTIVE: The molecular mechanisms underlying the association between obesity (BMI ≥ 30 kg/m(2)) and asthma are poorly understood. Since shifts in the fate of bronchial cells due to low-grade systemic inflammation may provide a possible explanation, we investigated whether two of the best documented functional variants in cell cycle control genes modify the obesity-asthma association. METHODS: We genotyped 5930...

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Source

Identifiers

PMID: 23311506
DOI: 10.3109/02770903.2012.757776

Genes

CCND1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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