Article
Significant Association of Cyclin D1 Promoter Genotypes With Asthma Susceptibility in Taiwan.
In vivo (Athens, Greece) - 1 Jan 2000
Li Chia-Hsiang, Chiu Kuo-Liang, Hsia Te-Chun, Shen Te-Chun, Chen Li-Hsiou, Yu Chien-Chih, Mong Mei-Chin, Chang Wen-Shin, Tsai Chia-Wen, Bau DA-Tian
Abstract excerpt
BACKGROUND/AIM: The molecular mechanisms underlying the association between cell cycle and asthma are poorly understood, and cyclin D1 (CCND1) is found to be upregulated in asthma airway smooth muscle. We investigated whether the most frequently examined functional variants in CCND1 determine asthma susceptibility. MATERIALS AND METHODS: We genotyped 651 participants for single-nucleotide polymorphisms (SNPs) at...
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