Article
CITED1 expression in liver development and hepatoblastoma.
Neoplasia (New York, N.Y.) - 1 Dec 2012
Murphy Andrew J, de Caestecker Christian, Pierce Janene, Boyle Scott C, Ayers Gregory D, Zhao Zhiguo, Libes Jaime M, Correa Hernan, Walter Teagan, Huppert Stacey S, Perantoni Alan O, de Caestecker Mark P, Lovvorn Harold N
Abstract excerpt
Hepatoblastoma, the most common pediatric liver cancer, consists of epithelial mixed embryonal/fetal (EMEF) and pure fetal histologic subtypes, with the latter exhibiting a more favorable prognosis. Few embryonal histology markers that yield insight into the biologic basis for this prognostic discrepancy exist. CBP/P-300 interacting transactivator 1 (CITED1), a transcriptional co-activator, is expressed in the...
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