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Article

Monitoring of Gaucher patients with a novel chitotriosidase assay.

Clinica chimica acta; international journal of clinical chemistry - 1 Jun 2007

Schoonhoven Aricha, Rudensky Bernard, Elstein Debbie, Zimran Ari, Hollak Carla E M, Groener Johanna E, Aerts Johannes M F G

Abstract excerpt

BACKGROUND: Chitotriosidase (CT) is a surrogate plasma marker for Gaucher disease. The enzyme is released by storage cells and is on average thousand fold elevated in serum of Gaucher patients. Plasma CT level is measured with the substrate 4-methylumbelliferyl (4MU)-chitotriose or 4MU-chitobiose. Given the limitations associated with the use of these substrates, a novel substrate, 4MU-deoxychitobiose, has...

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Identifiers

PMID: 17408605
DOI: 10.1016/j.cca.2007.02.042

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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