Fine mapping of a region of chromosome 11q23.3 reveals independent locus associated with risk of glioma.

doi:10.1371/journal.pone.0052864

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Article

Fine mapping of a region of chromosome 11q23.3 reveals independent locus associated with risk of glioma.

PloS one - 1 Jan 2012

Chen Hongyan, Sun Bing, Zhao Yingjie, Song Xiao, Fan Weiwei, Zhou Keke, Zhou Liangfu, Mao Ying, Lu Daru

Abstract excerpt

BACKGROUND: A single nucleotide polymorphism (SNP) at locus 11q23.3 (rs498872) in the near 5'-UTR of the PHLDB1 gene was recently implicated as a risk factor for gliomas in a genome-wide association study, and this involvement was confirmed in three additional studies. METHODOLOGY/PRINCIPAL FINDINGS: To identify possible causal variants in the region, the authors genotyped 15 tagging SNPs in the 200 kb genomic...

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Identifiers

PMID: 23300798
DOI: 10.1371/journal.pone.0052864
PMCID: PMC3534108

Genes

PHLDB1
ARCN1

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