Article
Robust and sensitive analysis of mouse knockout phenotypes.
PloS one - 1 Jan 2012
Karp Natasha A, Melvin David, Mott Richard F
Abstract excerpt
A significant challenge of in-vivo studies is the identification of phenotypes with a method that is robust and reliable. The challenge arises from practical issues that lead to experimental designs which are not ideal. Breeding issues, particularly in the presence of fertility or fecundity problems, frequently lead to data being collected in multiple batches. This problem is acute in high throughput phenotyping...
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