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Article

Optimising experimental design for high-throughput phenotyping in mice: a case study.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Oct 2010

Karp Natasha A, Baker Lauren A, Gerdin Anna-Karin B, Adams Niels C, Ramírez-Solis Ramiro, White Jacqueline K

Abstract excerpt

To further the functional annotation of the mammalian genome, the Sanger Mouse Genetics Programme aims to generate and characterise knockout mice in a high-throughput manner. Annually, approximately 200 lines of knockout mice will be characterised using a standardised battery of phenotyping tests covering key disease indications ranging from obesity to sensory acuity. From these findings secondary centres will...

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Identifiers

PMID: 20799038
DOI: 10.1007/s00335-010-9279-1
PMCID: PMC2974211

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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