Article
Transcriptomic analysis of PNN- and ESRP1-regulated alternative pre-mRNA splicing in human corneal epithelial cells.
Investigative ophthalmology & visual science - 23 Jan 2013
Joo Jeong-Hoon, Correia Greg P, Li Jian-Liang, Lopez Maria-Cecilia, Baker Henry V, Sugrue Stephen P
Abstract excerpt
PURPOSE: We investigated the impact of PININ (PNN) and epithelial splicing regulatory protein 1 (ESRP1) on alternative pre-mRNA splicing in the corneal epithelial context. METHODS: Isoform-specific RT-PCR assays were performed on wild-type and Pnn knockout mouse cornea. Protein interactions were...
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