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Article

Transcriptional profiling of corneal stromal cells derived from patients with keratoconus.

Scientific reports - 29 Aug 2019

Sharif Rabab, Khaled Mariam L, McKay Tina B, Liu Yutao, Karamichos Dimitrios

Abstract excerpt

Keratoconus (KC) is a multi-factorial corneal ectasia with unknown etiology affecting approximately 1:2000 people worldwide. Dysregulated gene expression, using RNA-Seq technology, have been reported in KC corneal tissue. However, the differential expression of genes, in KC corneal stromal cells have been widely ignored. We utilized mRNA-Seq to analyze gene expression in primary human corneal stromal cells...

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Identifiers

PMID: 31467338
DOI: 10.1038/s41598-019-48983-8
PMCID: PMC6715750

Genes

EGFR
HIF1A
HSPB1
LGALS3BP
MME
NEDD4
SDC2
SNTA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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