Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ovine forkhead box class O 3 (FOXO3) gene variation and its association with lifespan.

Molecular biology reports - 1 May 2013

Byun Seung Ok, Forrest Rachel H, Zhou Huitong, Frampton Chris M, Hickford Jon G H

Abstract excerpt

FOXO3 is a member of the FOXO (forkhead box class O) transcription factor family and has roles in cell cycle control, apoptosis, neural and hematopoietic cell differentiation and DNA repair among other functions. Several human studies provide evidence for an association between aging, longevity a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Motifs
Share to Forkhead Transcription Factors
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Order

Share to Haplotypes

Share to Longevity

Share to Sequence Alignment

Source

Identifiers

PMID: 23299403
DOI: 10.1007/s11033-012-2461-7

Genes

FOXO3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23299403-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ovine forkhead box class O 3 (FOXO3) gene variation and its association with lifespan.PMID 23299403Read ↗

Characterization of genetic variation in the Forkhead box class O3 gene (FOXO3) in sheep.Semantic proximity Read ↗

Replication of an association of variation in the FOXO3A gene with human longevity using both case-control and longitudinal data.Semantic proximity Read ↗

Association between FOXO3A gene polymorphisms and human longevity: a meta-analysis.Semantic proximity Read ↗

FOXO3 and Exceptional Longevity: Insights From Hydra to Humans.Semantic proximity Read ↗

Candidate gene study of FOXO1, FOXO4, and FOXO6 reveals no association with human longevity in GermansSemantic proximity Read ↗

Identification and characterization of two functional variants in the human longevity gene FOXO3.Semantic proximity Read ↗

FOXO3 and Related Transcription Factors in Development, Aging, and Exceptional LongevitySemantic proximity Read ↗

Novel protective effect of the FOXO3 longevity genotype on mechanisms of cellular aging in OkinawansSemantic proximity Read ↗

Genetic Association Analysis of Common Variants in FOXO3 Related to Longevity in a Chinese Population.Semantic proximity Read ↗

A mutation modulating DDX3Y gene expression cosegregates with the major Y-chromosomal haplogroups and with testis size in Hu sheep.Semantic proximity Read ↗

rs2802292 polymorphism in the FOXO3A gene and exceptional longevity in two ethnically distinct cohorts.Semantic proximity Read ↗

Mutations in the FOXO3 Gene and Their Effects on Meat Traits in Gannan Yaks.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.