Article
Genetic polymorphism for IFNγ +874T/A in patients with acute toxoplasmosis.
Revista da Sociedade Brasileira de Medicina Tropical - 1 Dec 2012
Neves Elizabeth de Souza, Curi André Luis Land, Albuquerque Maira Cavalcanti de, Palhano-Silva Cassius Schnel, Silva Laura Berriel da, Bueno Wendy Fernandes, Amendoeira Maria Regina Dos Reis, Bonecini-Almeida Maria da Gloria, Fernandes Octavio
Abstract excerpt
INTRODUCTION: A single nucleotide polymorphism (SNP) in the gene encoding gamma interferon influences its production and is associated with severity of infectious diseases. This study aimed to evaluate the association of IFNγ+874T/A SNP with duration of disease, morbidity, and development of retinochoroiditis in acute toxoplasmosis. METHODS: A case-control study was conducted among 30 patients and 90 controls....
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