Article
Interleukin-10 gene polymorphism (-1082G/A) is associated with toxoplasmic retinochoroiditis.
Investigative ophthalmology & visual science - 1 May 2008
Cordeiro Cynthia A, Moreira Paula R, Andrade Mariana S, Dutra Walderez O, Campos Wesley R, Oréfice Fernando, Teixeira Antônio L
Abstract excerpt
PURPOSE: Experimental data have demonstrated a relevant role for IL-10, an anti-inflammatory cytokine, in the modulation of acute ocular toxoplasmosis. Therefore, this study was conducted to investigate the possible association between an IL10 gene polymorphism at position -1082 and toxoplasmic retinochoroiditis (TR) in humans. METHODS: One hundred patients with diagnosed TR were recruited from the Uveitis...
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