Article
Dose response of soft X-ray-induced bystander cell killing affected by p53 status.
Radiation research - 1 Feb 2013
Tomita Masanori, Maeda Munetoshi, Kobayashi Katsumi, Matsumoto Hideki
Abstract excerpt
A radiation-induced bystander response, which is generally defined as a cellular response that is induced in nonirradiated cells that received bystander signals from directly irradiated cells within an irradiated cell population. In our earlier X-ray microbeam studies, bystander cell killing in normal human fibroblasts had a parabolic relationship to the irradiation dose. To elucidate the role of p53 in the...
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