Genetic dissection of a complex neurological mutant, polyhomeotic, in Drosophila.

doi:10.1016/0012-1606(90)90286-r

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Article

Genetic dissection of a complex neurological mutant, polyhomeotic, in Drosophila.

Developmental biology - 1 May 1990

Smouse D, Perrimon N

Abstract excerpt

Null mutations at the polyhomeotic locus of Drosophila produce a complex phenotype during embryogenesis, which includes death of the ventral epidermis, misregulation of homeotic and segmentation gene expression, and global misrouting of CNS axons. It is shown here, through the use of mosaic analy...

Topics

Animals
Axons
Brain
Cell Division
Cell Survival
Drosophila
Epidermal Cells
Epidermis
Gene Expression Regulation
Genes, Regulator
Mosaicism
Mutation
Neurons
Phenotype
Ring Chromosomes

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