Article
Genetic dissection of a complex neurological mutant, polyhomeotic, in Drosophila.
Developmental biology - 1 May 1990
Smouse D, Perrimon N
Abstract excerpt
Null mutations at the polyhomeotic locus of Drosophila produce a complex phenotype during embryogenesis, which includes death of the ventral epidermis, misregulation of homeotic and segmentation gene expression, and global misrouting of CNS axons. It is shown here, through the use of mosaic analyses, double mutant combinations, and in vitro culture experiments, that all aspects of the phenotype with the exception...
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