Article
Analysis of colorectal cancers in British Bangladeshi identifies early onset, frequent mucinous histotype and a high prevalence of RBFOX1 deletion.
Molecular cancer - 3 Jan 2013
Sengupta Neel, Yau Christopher, Sakthianandeswaren Anuratha, Mouradov Dmitri, Gibbs Peter, Suraweera Nirosha, Cazier Jean-Baptiste, Polanco-Echeverry Guadalupe, Ghosh Anil, Thaha Mohamed, Ahmed Shafi, Feakins Roger, Propper David, Dorudi Sina, Sieber Oliver, Silver Andrew, Lai Cecilia
Abstract excerpt
BACKGROUND: Prevalence of colorectal cancer (CRC) in the British Bangladeshi population (BAN) is low compared to British Caucasians (CAU). Genetic background may influence mutations and disease features. METHODS: We characterized the clinicopathological features of BAN CRCs and interrogated their genomes using mutation profiling and high-density single nucleotide polymorphism (SNP) arrays and compared findings to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.