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Article

PEP-1-CAT-transduced mesenchymal stem cells acquire an enhanced viability and promote ischemia-induced angiogenesis.

PloS one - 1 Jan 2012

Zhang Lei, Dong Xiao-Wei, Wang Jia-Ning, Tang Jun-Ming, Yang Jian-Ye, Guo Ling-Yun, Zheng Fei, Kong Xia, Huang Yong-Zhang, Chen Shi-You

Abstract excerpt

OBJECTIVE: Poor survival of mesenchymal stem cells (MSC) compromised the efficacy of stem cell therapy for ischemic diseases. The aim of this study is to investigate the role of PEP-1-CAT transduction in MSC survival and its effect on ischemia-induced angiogenesis. METHODS: MSC apoptosis was evaluated by DAPI staining and quantified by Annexin V and PI double staining and Flow Cytometry. Malondialdehyde (MDA)...

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Source

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Identifiers

PMID: 23285080
DOI: 10.1371/journal.pone.0052537
PMCID: PMC3532064

Genes

MSC
CAT
SRY

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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