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Hcp and VgrG1 are secreted components of the Helicobacter hepaticus type VI secretion system and VgrG1 increases the bacterial colitogenic potential.

Cellular microbiology - 1 Jun 2013

Bartonickova Lucie, Sterzenbach Torsten, Nell Sandra, Kops Friederike, Schulze Jessika, Venzke Annika, Brenneke Birgit, Bader Sophie, Gruber Achim D, Suerbaum Sebastian, Josenhans Christine

Abstract excerpt

The enterohepatic Epsilonproteobacterium Helicobacter hepaticus persistently colonizes the intestine of mice and causes chronic inflammatory symptoms in susceptible mouse strains. The bacterial factors causing intestinal inflammation are poorly characterized. A large genomic pathogenicity island, HHGI1, which encodes components of a type VI secretion system (T6SS), was previously shown to contribute to the...

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PMID: 23278999
DOI: 10.1111/cmi.12094

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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