Article
The type VI secretion system encoded in SPI-6 plays a role in gastrointestinal colonization and systemic spread of Salmonella enterica serovar Typhimurium in the chicken.
PloS one - 1 Jan 2013
Pezoa David, Yang Hee-Jeong, Blondel Carlos J, Santiviago Carlos A, Andrews-Polymenis Helene L, Contreras Inés
Abstract excerpt
The role of the Salmonella Pathogenicity Islands (SPIs) in pathogenesis of Salmonella enterica Typhimurium infection in the chicken is poorly studied, while many studies have been completed in murine models. The Type VI Secretion System (T6SS) is a recently described protein secretion system in Gram-negative bacteria. The genus Salmonella contains five phylogenetically distinct T6SS encoded in differentially...
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