Article
Only one of the two type VI secretion systems encoded in the Salmonella enterica serotype Dublin genome is involved in colonization of the avian and murine hosts.
Veterinary research - 9 Jan 2014
Pezoa David, Blondel Carlos J, Silva Cecilia A, Yang Hee-Jeong, Andrews-Polymenis Helene, Santiviago Carlos A, Contreras Inés
Abstract excerpt
The type VI secretion system (T6SS) is a virulence factor for many Gram-negative bacteria. Salmonella genus harbors five phylogenetically distinct T6SS loci encoded in Salmonella Pathogenicity Islands (SPIs) SPI-6, SPI-19, SPI-20, SPI-21 and SPI-22, which are differentially distributed among serotypes. The T6SSs encoded in SPI-6 and SPI-19 contribute to pathogenesis of serotypes Typhimurium and Gallinarum in mice...
Topics
- Animals
- Bacterial Secretion Systems
- Chickens
- Digestive System
- Genomic Islands
- Mice
- Mutation
- Salmonella enterica
- Spleen
- Virulence Factors