Article
PON1-108 TT and PON1-192 RR genotypes are more frequently encountered in Greek PCOS than non-PCOS women, and are associated with hyperandrogenaemia.
Clinical endocrinology - 1 Aug 2013
Paltoglou George, Tavernarakis George, Christopoulos Panagiotis, Vlassi Margarita, Gazouli Maria, Deligeoroglou Efthimios, Creatsas George, Mastorakos George
Abstract excerpt
OBJECTIVE: To investigate the frequencies of three paraoxonase (PON)1 polymorphisms in Greek polycystic ovary syndrome (PCOS) and non-PCOS women, and their genotypes association with hyperandrogenaemia and insulin resistance. DESIGN: Case-control genetic association study. SETTING: University Hospital Endocrine Unit. PATIENTS: A total of 142 PCOS cases (NIH criteria) and 112 controls. MAIN OUTCOME MEASURE:...
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