Article
Morphometrics of complex cell shapes: lobe contribution elliptic Fourier analysis (LOCO-EFA).
Development (Cambridge, England) - 20 Mar 2018
Sánchez-Corrales Yara E, Hartley Matthew, van Rooij Jop, Marée Athanasius F M, Grieneisen Verônica A
Abstract excerpt
Quantifying cell morphology is fundamental to the statistical study of cell populations, and can help unravel mechanisms underlying cell and tissue morphogenesis. Current methods, however, require extensive human intervention, are highly parameter sensitive, or produce metrics that are difficult to interpret biologically. We therefore developed a method, lobe contribution elliptical Fourier analysis (LOCO-EFA),...
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