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Article

Hepatitis B e antigen levels and response to peginterferon: influence of precore and basal core promoter mutants.

Antiviral research - 1 Mar 2013

Sonneveld Milan J, Rijckborst Vincent, Zwang Louwerens, Zeuzem Stefan, Jenny Heathcote E, Simon Krzysztof, Zoutendijk Roeland, Akarca Ulus S, Pas Suzan D, Hansen Bettina E, Janssen Harry L A

Abstract excerpt

Hepatitis B e antigen (HBeAg) levels may predict response to peginterferon (PEG-IFN) but are also influenced by presence of precore (PC) and core promoter (BCP) mutants. HBeAg was measured in 214 patients treated with PEG-IFN±lamivudine for 52weeks. Patients were classified at baseline as wildtype (WT) or non-WT (detectable PC/BCP mutants). Combined response (HBeAg loss with HBV DNA<2000IU/mL), HBeAg response...

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Identifiers

PMID: 23274785
DOI: 10.1016/j.antiviral.2012.12.023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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