Article
Hepatitis B virus genotype B results in better immediate, late and sustained responses to peginterferon-alfa in hepatitis-B-e-antigen-positive patients.
Journal of gastroenterology and hepatology - 1 Mar 2011
Chen Chien-Hung, Lee Chuan-Mo, Hung Chao-Hung, Wang Jing-Houng, Hu Tsung-Hui, Changchien Chi-Sin, Lu Sheng-Nan
Abstract excerpt
BACKGROUND AND AIMS: This study investigated outcome predictors in hepatitis-B-e-antigen (HBeAg)-positive chronic hepatitis B patients treated with peginterferon alfa-2a. METHODS: A total of 88 HBeAg-positive patients receiving peginterferon alfa-2a for 6 months and followed up for at least 24 weeks were prospectively analyzed. Precore and core promoter genes of hepatitis B virus (HBV) were sequenced from the...
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