Article
Role for phospholipid flippase complex of ATP8A1 and CDC50A proteins in cell migration.
The Journal of biological chemistry - 15 Feb 2013
Kato Utako, Inadome Hironori, Yamamoto Masatoshi, Emoto Kazuo, Kobayashi Toshihide, Umeda Masato
Abstract excerpt
Type IV P-type ATPases (P4-ATPases) and CDC50 family proteins form a putative phospholipid flippase complex that mediates the translocation of aminophospholipids such as phosphatidylserine (PS) and phosphatidylethanolamine (PE) from the outer to inner leaflets of the plasma membrane. In Chinese hamster ovary (CHO) cells, at least eight members of P4-ATPases were identified, but only a single CDC50 family protein,...
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