Article
Increase in serum brain-derived neurotrophic factor in met allele carriers of the BDNF Val66Met polymorphism is specific to males.
Neuropsychobiology - 1 Jun 2012
Bus Boudewijn A A, Arias-Vasquez Alejandro, Franke Barbara, Prickaerts Jos, de Graaf Jacqueline, Voshaar Richard C Oude
Abstract excerpt
BACKGROUND: Association studies of the Val66Met polymorphism and serum brain-derived neurotrophic factor (BDNF) levels have yielded conflicting results. Recently, sex-specific differences in BDNF levels were demonstrated. As these might explain the reported inconsistencies, we tested sex interactions with the Val66Met genotype on serum BDNF level. METHODS: Participants (n = 548, age range 50-72 years; mean 62.8 ±...
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