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Transfer of CD8+ T Cell Memory Using Bcl-2 as a Marker

26 Dec 2012

Abstract excerpt

The processes that regulate T cell memory generation are important for therapeutic design and the immune response to disease. However, what allows a subset of effector T cells to survive the contraction period to become memory cells is incompletely understood. The Bcl-2 family is critical for T cell survival, and Bcl-2 has been proposed to be important for the survival of memory cells. However, previous studies...

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PMID: 23269245
DOI: 10.4049/jimmunol.1103481

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