Article
Genetic variability of PRNP in Chinese indigenous goats.
Biochemical genetics - 1 Apr 2013
Zhou Rongyan, Li Xianglong, Xi Jianzhong, Li Lanhui, Zhang Zhenhong, Zhao Zhujun
Abstract excerpt
Polymorphism of the prion protein gene (PRNP) is usually associated with scrapie susceptibility or resistance. To determine the variability of PRNP in Chinese indigenous goat breeds, we isolated genomic DNA from goat blood and amplified and sequenced the coding region of the gene. We identified 10 polymorphic sites that gave rise to 28 haplotypes. Clear frequency differences were found between northern and...
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