Article
Exploring the toxicity of a bismuth-asparagine coordination polymer on the early development of zebrafish embryos.
Chemical research in toxicology - 18 Jan 2013
He Ningning, Li Xiang, Feng Daofu, Wu Ming, Chen Rui, Chen Tiehong, Chen Dongyan, Feng Xizeng
Abstract excerpt
Nanoparticles are widely used in nanomedicine, raising concerns about their toxicity. In this study, the toxicity of bismuth-asparagine coordination polymer spheres (BACP-2) was assessed in zebrafish embryos. Injection of 1-4 cell stage embryos with BACP-2 resulted in smaller head size (particularly smaller eye size), shorter body length, and pericardial edemas. The severity and occurrence of the resulting...
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