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Article

Matrix metalloproteinase-7 coordinates airway epithelial injury response and differentiation of ciliated cells.

American journal of respiratory cell and molecular biology - 1 Mar 2013

Gharib Sina A, Altemeier William A, Van Winkle Laura S, Plopper Charles G, Schlesinger Saundra Y, Buell Catherine A, Brauer Rena, Lee Vivian, Parks William C, Chen Peter

Abstract excerpt

Matrix metalloproteinase-7 (MMP7) expression is quickly up-regulated after injury, and functions to regulate wound repair and various mucosal immune processes. We evaluated the global transcriptional response of airway epithelial cells from wild-type and Mmp7-null mice cultured at an air-liquid interface. The analysis of differentially expressed genes between genotypes after injury revealed an enrichment of...

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Source

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Identifiers

PMID: 23258229
DOI: 10.1165/rcmb.2012-0083OC
PMCID: PMC3604090

Genes

MMP7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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