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Article

A genetic case-control study confirms the implication of SMAD7 and TNF locus in the development of proliferative vitreoretinopathy.

Investigative ophthalmology & visual science - 5 Mar 2013

Rojas Jimena, Fernandez Itziar, Pastor Jose C, Maclaren Robert E, Ramkissoon Yashim, Harsum Steven, Charteris David G, Van Meurs Jan C, Amarakoon Sankha, Ruiz-Moreno Jose M, Rocha-Sousa Amandio, Brion Maria, Carracedo Angel

Abstract excerpt

PURPOSE: Proliferative vitreoretinopathy (PVR) is still the major cause of failure of retinal detachment (RD) surgery and although the risk for developing this complication is associated with some clinical characteristics, the correlation is far from absolute, raising the possibility of genetic susceptibility. The objective of this study was to analyze the genetic contribution to PVR in patients undergoing RD...

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Identifiers

PMID: 23258148
DOI: 10.1167/iovs.12-10931

Genes

PVR
SMAD7
TNF

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