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Article

BAX and BCL-2 polymorphisms, as predictors of proliferative vitreoretinopathy development in patients suffering retinal detachment: the Retina 4 project.

Acta ophthalmologica - 1 Nov 2015

Pastor-Idoate Salvador, Rodríguez-Hernández Irene, Rojas Jimena, Fernández Itziar, García-Gutierrez María-Teresa, Ruiz-Moreno Jose M, Rocha-Sousa Amandio, Ramkissoon Yashin D, Harsum Steven, MacLaren Robert E, Charteris David G, Van Meurs Jan C, González-Sarmiento Rogelio, Pastor Jose C

Abstract excerpt

PURPOSE: To compare the distribution of BCL-2 -938C>A (rs2279115) and BAX -248G>A (rs4645878) genotypes among European subjects undergoing rhegmatogenous retinal detachment (RRD) surgery in relation to the further development of proliferative vitreoretinopathy (PVR). METHODS: A case-control gene association study, as a part of Retina 4 project, was designed. rs2279115 and rs4645878 polymorphisms were analysed in...

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Share to Apoptosis
Share to bcl-2-Associated X Protein
Share to Gene Frequency
Share to Genetic Markers
Share to Polymorphism, Single Nucleotide
Share to Proto-Oncogene Proteins c-bcl-2
Share to Retinal Detachment
Share to Risk Factors

Source

Identifiers

PMID: 25991504
DOI: 10.1111/aos.12718

Genes

BAX
PVR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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