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Article

A strong genetic association between the tumor necrosis factor locus and proliferative vitreoretinopathy: the retina 4 project.

Ophthalmology - 1 Dec 2010

Rojas Jimena, Fernandez Itziar, Pastor Jose C, Garcia-Gutierrez Maria T, Sanabria Maria R, Brion Maria, Coco Rosa M, Ruiz-Moreno Jose M, Garcia-Arumi Jose, Elizalde Javier, Ruiz-Miguel Miguel, Gallardo Jose M, Corrales Rosa M, Carracedo Angel

Abstract excerpt

OBJECTIVE: To assess the genetic contribution to proliferative vitreoretinopathy (PVR) and report the strong association observed in the tumor necrosis factor (TNF) locus. DESIGN: As a component of The Retina 4 Project, a case-controlled, candidate gene association study in the TNF locus was conducted. PARTICIPANTS AND CONTROLS: Blood from 450 patients with (138 cases) and without (312 controls)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20663564
DOI: 10.1016/j.ophtha.2010.03.059

Genes

PVR
LTA
TNF
LST1
NCR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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