Article
Searching for candidate genes in acute lung injury: SNPs, Chips and PBEF.
Transactions of the American Clinical and Climatological Association - 1 Jan 2005
Garcia Joe G N
Abstract excerpt
Acute lung injury (ALI) is a devastating illness, occurring in the setting of sepsis, with genetic variations contributing to ALI susceptibility and severity. We utilized the "candidate gene approach" with extensive expression profiling in animal and human ALI models to identify novel candidate genes. We noted significant expression of pre-B-cell colony enhancing factor (PBEF), a gene not previously associated...
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