Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SOX4 Transcriptionally Regulates Multiple SEMA3/Plexin Family Members and Promotes Tumor Growth in Pancreatic Cancer

12 Dec 2012

Abstract excerpt

Semaphorin signaling through Plexin frequently participates in tumorigenesis and malignant progression in various types of cancer. In particular, the role of semaphorin signaling in pancreatic ductal adenocarcinoma (PDAC) remains unexplored, despite a high likelihood of metastasis and mortality. Unlike other epithelial malignancies that often express a small number of specific genes in the Semaphorin/Plexin...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Axon Guidance and Neuronal Signaling
Share to Cancer-related Molecular Pathways
Share to FOXO transcription factor regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23251334
DOI: 10.1371/journal.pone.0048637

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SOX4 Transcriptionally Regulates Multiple SEMA3/Plexin Family Members and Promotes Tumor Growth in Pancreatic CancerPMID 23251334Read ↗

SOX9 is a critical regulator of TSPAN8-mediated metastasis in pancreatic cancerSemantic proximity Read ↗

SOX9 regulates ERBB signalling in pancreatic cancer developmentSemantic proximity Read ↗

Pan-Cancer Analysis Reveals SOX2 as a Promising Prognostic and Immunotherapeutic Biomarker Across Various Cancer Types, Including Pancreatic CancerSemantic proximity Read ↗

Molecular profiling of the "plexinome" in melanoma and pancreatic cancer.Semantic proximity Read ↗

Epigenetic Regulation of SOX9 by the NF-κB Signaling Pathway in Pancreatic Cancer Stem CellsSemantic proximity Read ↗

Embryonic stem cell factors and pancreatic cancerSemantic proximity Read ↗

Potential regulatory mechanisms of hsa_circ_0131457/miR-636/SFRP2 inhibition of tumor progression in pancreatic ductus adenocarcinomaSemantic proximity Read ↗

hsa_circ_0131457 regulates SFRP2 through miR-636 to inhibit the invasion and metastasis of pancreatic cancerSemantic proximity Read ↗

Transcriptomic and CRISPR/Cas9 technologies reveal FOXA2 as a tumor suppressor gene in pancreatic cancerSemantic proximity Read ↗

Sox9: A Master Regulator of the Pancreatic ProgramSemantic proximity Read ↗

Sox9 coordinates a transcriptional network in pancreatic progenitor cellsSemantic proximity Read ↗

Silencing of microRNA-135b inhibits invasion, migration, and stemness of CD24+CD44+ pancreatic cancer stem cells through JADE-1-dependent AKT/mTOR pathwaySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.