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Article

Accumulation of numerical and structural chromosome imbalances in spermatozoa from reciprocal translocation carriers

18 Dec 2012

Abstract excerpt

STUDY QUESTION: Is there a relationship between the occurrence of specific segregation modes and the production of additional numerical abnormalities in spermatozoa from reciprocal translocation carriers? STUDY ANSWER: The production of aneuploid and diploid spermatozoa tends to be associated with an unbalanced segregation outcome of the rearranged chromosomes. WHAT IS KNOWN ALREADY: Carriers of reciprocal...

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PMID: 23250926
DOI: 10.1093/humrep/des431

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