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Article

The paternal effect of chromosome translocation carriers observed from meiotic segregation in embryos

28 May 2010

Abstract excerpt

BACKGROUND: Human translocation carriers may present alterations in meiosis. Understanding the mechanism of meiotic segregation of reciprocal translocations is important for estimation of the risk of either pregnancy loss or birth defects. The objective of this work was to estimate meiotic segregation rates in preimplantation embryos from preimplantation genetic diagnosis (PGD) cycles of female and male...

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Identifiers

PMID: 20511301
DOI: 10.1093/humrep/deq111

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